Hydrogen Water vs Alkaline Water: Health Benefits Compared

Hydrogen Water vs Alkaline Water: Health Benefits Compared

Introduction

In recent years, the debate surrounding hydrogen water vs alkaline water has gained significant attention in the health and wellness community. As consumers become increasingly health-conscious, the quest for enhanced hydration options has led to the emergence of these two types of water, each claiming unique benefits. This comprehensive article aims to explore the key differences, potential health benefits, and scientific evidence behind hydrogen water and alkaline water.

Hydrogen water is regular water infused with additional molecular hydrogen (H2), typically produced through electrolysis. This process splits water molecules, allowing hydrogen gas to recombine and dissolve into the water. On the other hand, alkaline water has a higher pH level (usually 8-9.5) due to the addition of alkaline minerals such as calcium and magnesium. It can be produced through electrolysis or by dissolving minerals into water (Jain et al., 2019).

The primary distinction between these two types of water lies in their composition and proposed mechanisms of action. Hydrogen water's potential benefits stem from its antioxidant properties, attributed to the presence of molecular hydrogen. In contrast, alkaline water's purported advantages are related to its higher pH and mineral content. While both types of water have garnered attention for their potential health benefits, it is crucial to examine the scientific evidence supporting these claims and consider individual health goals when making an informed choice.

Here is the main body of the article on hydrogen water vs alkaline water:

Understanding Hydrogen Water and Alkaline Water

Composition and Production

Hydrogen water and alkaline water are two distinct types of enhanced water that have gained popularity in recent years. To understand their differences, it's important to examine how each is composed and produced.

Hydrogen water is regular water that has been infused with additional molecular hydrogen (H2). The most common method of producing hydrogen water is through electrolysis. In this process, an electric current is passed through water, causing it to split into hydrogen and oxygen gases. The hydrogen gas is then dissolved back into the water, resulting in hydrogen-rich water. Some hydrogen water can contain up to 1.6 parts per million (ppm) of dissolved hydrogen gas (Ohta et al., 2011).

Alkaline water, on the other hand, is water with a higher pH level than regular drinking water. It typically has a pH between 8 and 9.5, compared to the neutral pH of 7 for regular water. Alkaline water can be produced through several methods:

  1. Electrolysis: Similar to hydrogen water production, electrolysis can be used to create alkaline water. In this case, the process separates water into acidic and alkaline components.

  2. Adding alkaline minerals: Minerals like calcium, potassium, and magnesium can be added to water to increase its pH level.

  3. Natural sources: Some spring waters are naturally alkaline due to the minerals they absorb from rocks and soil.

It's worth noting that while both hydrogen water and alkaline water can be produced through electrolysis, the focus and end result of the process differ for each type of water.

pH Levels

The pH level is a crucial factor in distinguishing between hydrogen water and alkaline water.

Hydrogen water typically maintains a neutral pH similar to regular water, around 7 on the pH scale. The addition of molecular hydrogen does not significantly alter the water's pH. This is because the dissolved hydrogen exists as neutral H2 molecules rather than hydrogen ions (H+) that would affect pH (Ohsawa et al., 2007).

Alkaline water, by definition, has a higher pH level than regular water. The pH of alkaline water usually ranges from 8 to 9.5, making it more basic on the pH scale. This increased alkalinity is due to the presence of alkaline minerals or the removal of acidic components during the production process.

The importance of pH in water relates to its potential effects on the body. Proponents of alkaline water argue that consuming water with a higher pH may help neutralize acid in the body, potentially offering health benefits. However, it's important to note that the body has robust systems in place to maintain its pH balance, and the effects of consuming alkaline water on overall body pH are still a subject of scientific debate (Fenton & Huang, 2016).

Key Properties

The key properties of hydrogen water and alkaline water stem from their unique compositions.

Hydrogen water's primary property is its high content of dissolved molecular hydrogen (H2). This gives hydrogen water potent antioxidant properties. Molecular hydrogen is a selective antioxidant, meaning it can neutralize harmful free radicals without affecting beneficial ones. This selectivity is what sets hydrogen apart from other antioxidants and is the basis for many of its proposed health benefits (Ohta, 2011).

The antioxidant action of hydrogen water occurs through several mechanisms:

  1. Direct neutralization of hydroxyl radicals (OH•), one of the most reactive and damaging free radicals.
  2. Indirect antioxidant effects by activating Nrf2, a transcription factor that regulates the expression of antioxidant proteins.
  3. Modulation of cell signaling pathways involved in inflammation and oxidative stress.

Alkaline water's key properties are related to its higher pH and mineral content. The alkalinity of the water is thought to:

  1. Help neutralize acid in the body, potentially alleviating symptoms of acid reflux or other acid-related issues.
  2. Provide beneficial minerals like calcium and magnesium, which may contribute to bone health and other bodily functions.
  3. Potentially improve hydration, although this claim is still under scientific scrutiny.

It's important to note that while both types of water have distinct properties, the extent of their effects on human health is still being researched, and more long-term studies are needed to fully understand their impacts.

Potential Health Benefits of Hydrogen Water

Antioxidant Effects

One of the most well-studied aspects of hydrogen water is its antioxidant properties. Molecular hydrogen (H2) acts as a selective antioxidant, targeting specifically harmful free radicals while leaving beneficial ones intact. This selectivity is crucial, as it allows hydrogen to potentially reduce oxidative stress without disrupting normal cellular functions.

The antioxidant mechanism of hydrogen water primarily involves:

  1. Direct neutralization of hydroxyl radicals (OH•): Hydrogen can selectively reduce the most cytotoxic free radicals, such as hydroxyl radicals, which are known to cause extensive cellular damage (Ohsawa et al., 2007).

  2. Activation of antioxidant pathways: Hydrogen has been shown to activate the Nrf2-Keap1 pathway, which regulates the expression of various antioxidant proteins, enhancing the body's natural antioxidant defenses (Iketani et al., 2017).

  3. Modulation of cell signaling: Hydrogen can influence various cell signaling pathways involved in oxidative stress and inflammation, potentially leading to cytoprotective effects (Ohta, 2011).

These antioxidant effects may have wide-ranging implications for health. Oxidative stress is implicated in numerous chronic diseases, including cardiovascular diseases, neurodegenerative disorders, and certain cancers. By potentially reducing oxidative stress, hydrogen water might offer protective effects against these conditions, although more research is needed to confirm these benefits in humans.

Inflammation Reduction

Closely related to its antioxidant effects, hydrogen water has shown potential in reducing inflammation. Chronic inflammation is a common factor in many diseases, and managing it is crucial for overall health.

Several studies have investigated the anti-inflammatory effects of hydrogen water:

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  1. A study on patients with rheumatoid arthritis found that drinking hydrogen water for four weeks reduced oxidative stress and improved disease activity (Ishibashi et al., 2012).

  2. In animal models of inflammatory bowel disease, hydrogen-rich water was shown to attenuate inflammation and oxidative stress in the colon (Shen et al., 2017).

  3. Research on athletes has suggested that hydrogen water may help reduce exercise-induced inflammation and oxidative stress (Aoki et al., 2012).

The mechanism behind hydrogen's anti-inflammatory effects is thought to involve the modulation of pro-inflammatory signaling pathways and the reduction of oxidative stress-induced inflammation. However, more large-scale human studies are needed to fully understand the extent and applicability of these effects.

Exercise Performance and Recovery

Hydrogen water has gained attention in the sports and fitness community for its potential to enhance exercise performance and recovery. Several studies have explored these effects:

  1. Fatigue Reduction: A study on elite athletes found that drinking hydrogen water for two weeks reduced lactic acid build-up during intense exercise and decreased overall fatigue (Aoki et al., 2012).

  2. Improved Recovery: Research has suggested that hydrogen water may help reduce muscle soreness and inflammation after intense exercise, potentially speeding up recovery times (Kawamura et al., 2016).

  3. Enhanced Performance: Some studies have reported improved exercise performance with hydrogen water consumption, although results have been mixed and more research is needed in this area (Mikami et al., 2019).

The potential benefits for athletes are thought to stem from hydrogen's ability to reduce oxidative stress and inflammation, which are both increased during intense physical activity. By mitigating these factors, hydrogen water may help maintain cellular function and energy production during exercise.

Other Potential Health Applications

Emerging research has explored the potential of hydrogen water in various other health conditions:

  1. Metabolic Syndrome: Some studies have suggested that hydrogen water may improve lipid and glucose metabolism in patients with metabolic syndrome or type 2 diabetes (Nakao et al., 2010).

  2. Neurological Disorders: Preliminary research has investigated the potential neuroprotective effects of hydrogen in conditions like Parkinson's disease and Alzheimer's disease, although human studies are limited (Fu et al., 2009).

  3. Cardiovascular Health: Animal studies have shown potential cardioprotective effects of hydrogen, but human research is still in early stages (Ohsawa et al., 2007).

  4. Cancer: Some preclinical studies have explored the potential of hydrogen in supporting cancer treatment, particularly in reducing side effects of chemotherapy and radiation therapy (Kang et al., 2011).

While these areas of research are promising, it's crucial to note that many of these studies are preliminary, often conducted in animal models or small human trials. Larger, long-term human studies are needed to confirm these potential benefits and understand the optimal use of hydrogen water for various health conditions.

Potential Health Benefits of Alkaline Water

Acid Neutralization

One of the primary proposed benefits of alkaline water is its potential to neutralize acid in the body. The theory behind this is that consuming water with a higher pH may help balance the body's acidity, particularly in the digestive system.

Some studies have explored this potential benefit:

  1. Acid Reflux: A study published in the Annals of Otology, Rhinology & Laryngology found that alkaline water with a pH of 8.8 may help deactivate pepsin, an enzyme involved in acid reflux (Koufman & Johnston, 2012). However, this was an in vitro study, and more research is needed to confirm these effects in humans.

  2. Digestive Health: Some proponents argue that alkaline water may help neutralize stomach acid, potentially alleviating symptoms of acid reflux or heartburn. However, it's important to note that stomach acid plays a crucial role in digestion and killing harmful bacteria, so altering its pH could have unintended consequences.

While these potential benefits are intriguing, it's crucial to understand that the body has robust systems in place to maintain its pH balance. The impact of alkaline water on overall body pH is likely to be minimal, as the body tightly regulates its pH through various buffering systems (Fenton & Huang, 2016).

Hydration and Mineral Absorption

Another area of interest regarding alkaline water is its potential effects on hydration and mineral absorption.

  1. Improved Hydration: Some studies have suggested that alkaline water may enhance hydration. A study published in the Journal of the International Society of Sports Nutrition found that alkaline water with a pH of 9.5 appeared to enhance hydration status after exercise-induced dehydration compared to regular water (Weidman et al., 2016). However, more research is needed to confirm these findings and understand the mechanisms involved.

  2. Mineral Absorption: Alkaline water often contains minerals like calcium and magnesium. Some proponents argue that these minerals may be more easily absorbed from alkaline water than from food sources. However, scientific evidence supporting this claim is limited, and more research is needed to confirm any enhanced mineral absorption from alkaline water.

It's important to note that while alkaline water may contain beneficial minerals, a balanced diet typically provides all the necessary minerals for good health. The potential benefits of alkaline water for mineral absorption should be considered in the context of overall nutritional intake.

Exercise-Related Benefits

Some research has explored the potential benefits of alkaline water for exercise performance and recovery:

  1. Lactic Acid Reduction: A small study published in the Journal of the International Society of Sports Nutrition found that consumption of alkaline water may help reduce blood lactate levels and improve hydration status during high-intensity interval training (Chycki et al., 2017). However, this study had a small sample size, and more research is needed to confirm these findings.

  2. Performance Enhancement: Some athletes and fitness enthusiasts claim that alkaline water improves their performance and recovery. However, scientific evidence supporting these claims is limited, and more rigorous studies are needed to establish any definitive benefits.

When comparing alkaline water to hydrogen water for exercise benefits, it's important to note that the mechanisms of action are different. While alkaline water's potential benefits are often attributed to its higher pH and mineral content, hydrogen water's effects are primarily linked to its antioxidant properties.

Other Proposed Benefits

Various other health claims have been made about alkaline water, including:

  1. Anti-aging effects: Some proponents suggest that alkaline water may slow the aging process by neutralizing free radicals. However, scientific evidence supporting this claim is lacking.

  2. Cancer prevention: Claims have been made about alkaline water's potential to prevent or treat cancer by creating an alkaline environment in the body. However, these claims are not supported by scientific evidence, and cancer experts emphasize that cancer cells can grow in any pH environment (American Institute for Cancer Research, 2019).

  3. Weight loss: Some suggest that alkaline water may aid in weight loss by improving metabolism. However, there is no substantial scientific evidence to support this claim.

  4. Bone health: Due to its mineral content, some propose that alkaline water may benefit bone health. While adequate mineral intake is important for bone health, evidence specifically supporting alkaline water for this purpose is limited.

It's crucial to approach these claims with caution. While alkaline water is generally considered safe for most people, the scientific evidence supporting many of its purported health benefits is limited. More rigorous, long-term studies are needed to fully understand the potential effects of alkaline water on various aspects of health.

Comparing Hydrogen Water and Alkaline Water

Key Differences

When comparing hydrogen water and alkaline water, several key differences emerge:

  1. Primary Mechanisms of Action:

    • Hydrogen Water: The main active component is dissolved molecular hydrogen (H2), which acts as a selective antioxidant.
    • Alkaline Water: The primary feature is its higher pH level and mineral content.
  2. pH Levels:

    • Hydrogen Water: Typically has a neutral pH similar to regular water (around 7).
    • Alkaline Water: Has a higher pH, usually between 8 and 9.5.
  3. Antioxidant Properties:

    • Hydrogen Water: Offers potent antioxidant effects due to the presence of molecular hydrogen.
    • Alkaline Water: May have some antioxidant properties due to its mineral content, but this is not its primary feature.
  4. Mineral Content:

    • Hydrogen Water: Does not necessarily contain additional minerals.
    • Alkaline Water: Often contains added minerals like calcium and magnesium.
  5. Production Methods:

    • Hydrogen Water: Typically produced through electrolysis to infuse water with hydrogen gas.
    • Alkaline Water: Can be produced through electrolysis, addition of minerals, or sourced naturally.
  6. Availability:

    • Hydrogen Water: Often available in specialized bottles or can be produced at home with hydrogen water generators.
    • Alkaline Water: More widely available, including bottled versions and home water ionizers.

Scientific Evidence

The body of scientific research for hydrogen water and alkaline water differs in scope and depth:

Hydrogen Water: - More extensive research has been conducted on hydrogen water, particularly in Japan and other Asian countries. - Several clinical trials have explored its potential benefits, including its effects on oxidative stress, inflammation, and various health conditions. - A meta-analysis published in the journal Oncotarget reviewed 60 studies on molecular hydrogen and found promising results for its therapeutic potential in various diseases (Ichihara et al., 2015).

Alkaline Water: - Research on alkaline water is more limited compared to hydrogen water. - Some studies have explored its potential benefits for acid reflux and hydration, but large-scale, long-term studies are lacking. - A review published in the Journal of the International Society of Sports Nutrition concluded that there is a lack of evidence to support the use of alkaline water for the prevention of cancer and other chronic diseases (Fenton & Huang, 2016).

When comparing the strength of evidence, hydrogen water currently has a more robust scientific backing for its potential health benefits. However, it's important to note that research in both areas is ongoing, and our understanding may evolve with future studies.

Safety Considerations

Both hydrogen water and alkaline water are generally considered safe for most people when consumed in moderation. However, there are some safety considerations to keep in mind:

Hydrogen Water: - No significant side effects have been reported in studies on hydrogen water consumption. - The dissolved hydrogen gas is considered safe and is naturally produced in small amounts by gut bacteria.

Alkaline Water: - While generally safe, excessive consumption of alkaline water may lead to: 1. Reduction of stomach acidity, which could interfere with digestion and the body's ability to kill harmful bacteria. 2. Metabolic alkalosis, a condition where the body's pH becomes too alkaline, potentially causing symptoms like nausea, vomiting, and confusion (Wynn et al., 2009). 3. Mineral imbalances if consumed in very large quantities over long periods.

For both types of water, it's important to maintain a balance and not rely on them as a sole source of hydration. Regular water should still form the basis of daily fluid intake. As with any significant change to diet or lifestyle, it's advisable to consult with a healthcare professional, especially for individuals with pre-existing health conditions or those taking medications.

Making an Informed Choice

Considering Individual Health Goals

When deciding between hydrogen water and alkaline water, it's crucial to consider your specific health objectives:

  1. Antioxidant Support: If your primary goal is to increase antioxidant intake, hydrogen water may be more suitable due to its potent antioxidant properties.

  2. Digestive Issues: For those dealing with acid reflux or

Conclusion

The comparison between hydrogen water and alkaline water reveals two distinct approaches to enhanced hydration, each with its own proposed benefits and mechanisms of action. While both types of water have garnered attention in the health and wellness community, the scientific evidence supporting their claims varies significantly.

Hydrogen water, with its dissolved molecular hydrogen, has shown promising results in numerous studies, particularly in areas related to antioxidant effects, inflammation reduction, and exercise performance. The selective antioxidant properties of molecular hydrogen offer a unique approach to combating oxidative stress without interfering with beneficial cellular processes. However, more large-scale, long-term human studies are needed to fully establish its efficacy across various health conditions.

Alkaline water, on the other hand, has a more limited body of research supporting its health claims. While some studies suggest potential benefits for acid reflux and hydration, the overall evidence is less robust compared to hydrogen water. The body's natural pH regulation mechanisms also raise questions about the long-term effects of consuming high-pH water.

When considering which type of water to incorporate into your lifestyle, it's crucial to align your choice with your specific health goals and consult with healthcare professionals. For those primarily seeking antioxidant support or potential benefits in exercise recovery, hydrogen water may be the more suitable option. Individuals dealing with acid reflux or seeking to increase mineral intake might find alkaline water more appealing, though caution should be exercised to avoid excessive consumption.

Ultimately, both hydrogen water and alkaline water should be viewed as potential supplements to a healthy lifestyle rather than miracle solutions. A balanced diet, regular exercise, and adequate hydration with plain water remain the cornerstones of good health. As research in this field continues to evolve, staying informed about the latest scientific findings will be key to making the best choices for your individual health needs.

Key Highlights and Actionable Tips

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• Hydrogen water contains dissolved molecular hydrogen (H2) which acts as a selective antioxidant, while alkaline water has a higher pH level (8-9.5) due to added minerals.

• Hydrogen water maintains a neutral pH around 7, while alkaline water is more basic with a pH of 8-9.5.

• Hydrogen water shows more robust scientific evidence for potential health benefits, particularly for antioxidant effects and exercise performance.

• Alkaline water has more limited research but may help with acid reflux symptoms and hydration.

• Consider your specific health goals when choosing - hydrogen water may be better for antioxidant support, while alkaline water could help with digestive issues.

• Consult a healthcare professional before making significant changes to your hydration routine, especially if you have pre-existing conditions.

• Maintain balance by not relying solely on enhanced waters - regular water should still be your primary source of hydration.

• Stay informed about ongoing research, as our understanding of these waters' effects continues to evolve.

Is hydrogen water safe for everyone to consume?

While hydrogen water is generally considered safe for most people, it's always wise to consult with a healthcare professional before making significant changes to your diet or hydration routine. This is particularly important for individuals with pre-existing health conditions or those taking medications. Currently, no significant side effects have been reported in studies on hydrogen water consumption. However, as with any supplement, moderation is key. It's also worth noting that pregnant women, children, and individuals with specific health concerns should seek medical advice before incorporating hydrogen water into their routine.

How long does hydrogen water maintain its beneficial properties?

The stability of dissolved hydrogen in water is a crucial factor to consider. Once hydrogen is dissolved in water, it begins to dissipate over time, especially when exposed to air. Generally, hydrogen-rich water maintains its beneficial properties for about 1-2 hours after opening the container. Some manufacturers have developed specialised packaging or bottles designed to maintain hydrogen concentration for longer periods. If you're using a hydrogen water generator at home, it's best to consume the water shortly after production to ensure maximum benefit. Always check the manufacturer's guidelines for specific storage and consumption recommendations.

Can alkaline water interfere with medication absorption?

This is an important consideration for those on regular medication. Alkaline water could potentially affect the absorption of certain medications, particularly those that are designed to be absorbed in an acidic environment. For example, some medications are coated to protect them from stomach acid, allowing them to be absorbed in the small intestine. Consuming alkaline water with these medications might interfere with this process. It's crucial to consult with your healthcare provider or pharmacist about the potential interactions between alkaline water and your specific medications. They may advise leaving a gap between taking medication and drinking alkaline water to ensure optimal absorption.

How does the environmental impact of hydrogen water compare to alkaline water?

The environmental considerations of these enhanced waters are an important aspect that consumers are increasingly interested in. The production of both hydrogen and alkaline water typically requires specialised equipment and energy input, which can have environmental implications. Hydrogen water production often involves electrolysis, which requires electricity. The environmental impact would depend on the source of this electricity (renewable vs non-renewable). Alkaline water can be produced through various methods, including electrolysis and mineral addition. Some alkaline water is sourced from natural springs, which may have a lower environmental impact. However, bottled versions of both types of water contribute to plastic waste. Home systems for producing these waters might have a lower long-term environmental impact compared to bottled versions, but they still require energy to operate. When considering environmental impact, it's worth looking at the entire lifecycle of the product, from production to packaging and distribution.

Can hydrogen water or alkaline water replace electrolyte drinks for athletes?

While both hydrogen water and alkaline water have been studied for potential benefits in exercise performance and recovery, they are not direct replacements for electrolyte drinks. Electrolyte drinks are specifically formulated to replace fluids and electrolytes lost through sweat during intense exercise. Hydrogen water's potential benefits for athletes are primarily related to its antioxidant properties, which may help reduce exercise-induced oxidative stress and inflammation (Aoki et al., 2012). Alkaline water has been studied for potential improvements in hydration status (Weidman et al., 2016). However, neither typically contains the balanced electrolyte profile found in sports drinks. Athletes engaging in prolonged or intense exercise should consult with a sports nutritionist or dietitian to determine the most appropriate hydration strategy, which may involve a combination of different fluids to meet their specific needs.

References (Click to Expand)

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Chycki, J., Zając, T., Maszczyk, A., & Kurylas, A. (2017). The effect of mineral-based alkaline water on hydration status and the metabolic response to short-term anaerobic exercise. Biology of Sport, 34(3), 255-261. https://doi.org/10.5114/biolsport.2017.66003

Fenton, T. R., & Huang, T. (2016). Systematic review of the association between dietary acid load, alkaline water and cancer. BMJ Open, 6(6), e010438. https://doi.org/10.1136/bmjopen-2015-010438

Fu, Y., Ito, M., Fujita, Y., Ito, M., Ichihara, M., Masuda, A., Suzuki, Y., Maesawa, S., Kajita, Y., Hirayama, M., Ohsawa, I., Ohta, S., & Ohno, K. (2009). Molecular hydrogen is protective against 6-hydroxydopamine-induced nigrostriatal degeneration in a rat model of Parkinson's disease. Neuroscience Letters, 453(2), 81-85. https://doi.org/10.1016/j.neulet.2009.02.016

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Iketani, M., Ohsawa, I., Takahashi, K., Tanaka, Y., Sato, Y., Yamaguchi, T., Nakahata, N., & Ohta, S. (2017). Nrf2 activation protects against renal ischemia-reperfusion injury through regulation of antioxidant enzymes. Free Radical Biology and Medicine, 108, 1-10. https://doi.org/10.1016/j.freeradbiomed.2017.03.013

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Jain, S. K., Parsanathan, R., Achari, A. E., Kanikarla-Marie, P., & Bocchini, J. A. (2019). Glutathione Stimulates Vitamin D Regulatory and Glucose-Metabolism Genes, Lowers Oxidative Stress and Inflammation, and Increases 25-Hydroxy-Vitamin D Levels in Blood: A Novel Approach to Treat 25-Hydroxyvitamin D Deficiency. Antioxidants & Redox Signaling, 30(17), 1890-1904. https://doi.org/10.1089/ars.2018.7506

Kang, K. M., Kang, Y. N., Choi, I. B., Gu, Y., Kawamura, T., Toyoda, Y., & Nakao, A. (2011). Effects of drinking hydrogen-rich water on the quality of life of patients treated with radiotherapy for liver tumors. Medical Gas Research, 1(1), 11. https://doi.org/10.1186/2045-9912-1-11

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Mikami, T., Tano, K., Lee, H., Lee, H., Park, J., Ohta, F., Bonkohara, Y., Ohta, S., & Kawamura, T. (2019). Drinking hydrogen water enhances endurance and relieves psychometric fatigue: a randomized, double-blind, placebo-controlled study. Canadian Journal of Physiology and Pharmacology, 97(9), 857-862. https://doi.org/10.1139/cjpp-2019-0059

Nakao, A., Toyoda, Y., Sharma, P., Evans, M., & Guthrie, N. (2010). Effectiveness of hydrogen rich water on antioxidant status of subjects with potential metabolic syndrome—an open label pilot study. Journal of Clinical Biochemistry and Nutrition, 46(2), 140-149. https://doi.org/10.3164/jcbn.09-100

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Shen, N. Y., Bi, J. B., Zhang, J. Y., Zhang, S. M., Gu, J. X., Qu, K., & Liu, C. (2017). Hydrogen-rich water protects against inflammatory bowel disease in mice by inhibiting endoplasmic reticulum stress and promoting heme oxygenase-1 expression. World Journal of Gastroenterology, 23(8), 1375-1386. https://doi.org/10.3748/wjg.v23.i8.1375

Weidman, J., Holsworth, R. E., Brossman, B., Cho, D. J., St Cyr, J., & Fridman, G. (2016). Effect of electrolyzed high-pH alkaline water on blood viscosity in healthy adults. Journal of the International Society of Sports Nutrition, 13, 45. https://doi.org/10.1186/s12970-016-0153-8

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