Introduction
Cherry juice, particularly tart cherry juice, has gained significant attention in recent years for its potential health benefits. This natural beverage, derived from the fruit of Prunus cerasus trees, has been the subject of numerous scientific studies exploring its effects on various aspects of human health. The cherry juice benefits range from improved sleep quality to enhanced exercise recovery, making it an intriguing option for those seeking natural ways to support their wellbeing.
The nutritional profile of cherry juice is impressive, boasting a rich array of vitamins, minerals, and antioxidants. Of particular interest are the anthocyanins, powerful plant compounds that give cherries their deep red colour and are responsible for many of their purported health benefits. These bioactive components have been shown to possess anti-inflammatory and antioxidant properties, which may contribute to the wide-ranging effects observed in clinical studies (Kelley et al., 2018).
One of the most well-researched cherry juice benefits is its potential to improve sleep quality. A randomised, double-blind, placebo-controlled study by Pigeon et al. (2010) found that adults with insomnia who consumed tart cherry juice twice daily for two weeks experienced significant improvements in sleep duration and quality. The researchers attributed these effects to the presence of melatonin and tryptophan in cherry juice, both of which play crucial roles in regulating sleep patterns. Furthermore, a more recent study by Losso et al. (2018) corroborated these findings, demonstrating that tart cherry juice consumption led to increased sleep time and efficiency in older adults with insomnia.
Here is the main body content for the comprehensive article on cherry juice benefits:
Types of Cherry Juice
Cherry juice comes in several varieties, each with its own unique flavor profile and potential health benefits. Understanding the different types can help you choose the best option for your needs.
Tart Cherry Juice
Tart cherry juice, derived from Montmorency or Balaton cherries, is the most extensively studied variety for its health benefits. It has a distinctly sour taste and is rich in anthocyanins, which give it potent antioxidant and anti-inflammatory properties. Tart cherry juice is often the focus of research on sleep improvement, exercise recovery, and pain reduction (Kelley et al., 2018).
Black Cherry Juice
Black cherry juice, made from sweet black cherries, has a milder, sweeter flavor compared to tart cherry juice. While not as widely studied as tart cherry juice, black cherry juice still contains beneficial antioxidants and may offer similar health benefits, albeit potentially to a lesser degree (Chai et al., 2019).
Sour Cherry Juice
Sour cherry juice, sometimes used interchangeably with tart cherry juice, is made from varieties like the Morello cherry. It shares many of the same properties as tart cherry juice and is often used for similar health purposes (Losso et al., 2018).
Pure Cherry Juice
Pure cherry juice refers to 100% cherry juice without any added sugars or preservatives. This can be made from any variety of cherry but is most commonly found in tart or black cherry varieties. Pure cherry juice preserves the full nutritional profile of the fruit and is often recommended for those seeking the maximum potential health benefits (Kent et al., 2017).
Nutritional Profile of Cherry Juice
Cherry juice boasts an impressive array of nutrients that contribute to its potential health benefits. Understanding this nutritional profile helps explain why cherry juice has garnered so much attention in the health and wellness community.
Vitamins and Minerals
Cherry juice is a good source of several essential vitamins and minerals:
- Vitamin C: An important antioxidant that supports immune function and skin health.
- Vitamin A: Crucial for eye health and immune function.
- Potassium: Essential for heart health and blood pressure regulation.
- Manganese: Important for metabolism and bone formation.
- Copper: Necessary for forming red blood cells and maintaining nerve cells and the immune system.
A study by Kelley et al. (2018) found that a 240 ml serving of tart cherry juice provides about 62% of the daily recommended intake of vitamin A and 40% of vitamin C.
Antioxidants
One of the most significant aspects of cherry juice's nutritional profile is its high antioxidant content. Antioxidants are compounds that help protect your cells against damage from free radicals, which are unstable molecules that can contribute to chronic diseases and aging.
Cherry juice is particularly rich in flavonoids, a type of antioxidant. A study by Kent et al. (2017) found that cherry juice had a higher antioxidant capacity than many other fruit juices, including apple, pomegranate, and acai berry juice.
Anthocyanins
Anthocyanins are a specific type of flavonoid that give cherries their deep red color. These compounds have been the focus of much research due to their potent antioxidant and anti-inflammatory properties.
Tart cherries, in particular, are rich in anthocyanins. A study by Chai et al. (2019) found that tart cherry juice contained significantly higher levels of anthocyanins compared to sweet cherry varieties. These anthocyanins are believed to be responsible for many of the potential health benefits associated with cherry juice consumption.
Sleep Improvement Benefits of Cherry Juice
One of the most well-researched benefits of cherry juice, particularly tart cherry juice, is its potential to improve sleep quality and duration. This effect is attributed to the unique nutritional composition of cherries.
Melatonin and Tryptophan Content
Cherry juice, especially tart cherry juice, is a natural source of melatonin and tryptophan, two compounds crucial for regulating sleep patterns:
Melatonin: Often referred to as the "sleep hormone," melatonin is naturally produced by the body to regulate the sleep-wake cycle. Tart cherries are one of the few known food sources of melatonin.
Tryptophan: An essential amino acid that the body uses to produce serotonin, which can then be converted to melatonin.
A study by Losso et al. (2018) found that tart cherry juice contains about 13 nanograms of melatonin per gram and about 9 milligrams of tryptophan per 100 grams.
Research on Cherry Juice and Sleep
Several studies have investigated the effects of cherry juice on sleep:
Pigeon et al. (2010) conducted a randomized, double-blind, placebo-controlled study on adults with chronic insomnia. Participants who consumed tart cherry juice twice daily for two weeks experienced significant improvements in sleep efficiency and total sleep time compared to those who received a placebo.
In a more recent study, Losso et al. (2018) found that older adults with insomnia who drank tart cherry juice for two weeks increased their sleep time by an average of 84 minutes per night compared to a placebo group.
These studies suggest that the melatonin and tryptophan in cherry juice may help regulate sleep patterns and improve overall sleep quality.
Recommended Dosage for Sleep Benefits
While optimal dosage can vary depending on individual factors, most studies have used the following protocol:
- Timing: Consume cherry juice twice daily, once in the morning and once 1-2 hours before bedtime.
- Quantity: Most studies used 240 ml (about 8 ounces) of tart cherry juice per serving.
It's important to note that while these dosages have shown benefits in studies, individuals should consult with a healthcare provider before using cherry juice as a sleep aid, especially if they have existing health conditions or are taking medications.
Exercise Recovery and Performance Enhancement
Cherry juice, particularly tart cherry juice, has gained popularity among athletes and fitness enthusiasts for its potential to aid in exercise recovery and enhance performance. This benefit is largely attributed to the anti-inflammatory and antioxidant properties of cherries.
Anti-Inflammatory Properties of Cherry Juice
The anthocyanins in cherry juice have potent anti-inflammatory effects, which may help reduce exercise-induced muscle damage and inflammation. A landmark study by Connolly et al. (2006) found that participants who consumed tart cherry juice before and after eccentric exercise experienced less muscle damage and strength loss compared to those who received a placebo.
The anti-inflammatory effects of cherry juice may be comparable to some over-the-counter medications. Kuehl et al. (2010) found that runners who consumed tart cherry juice for seven days prior to and on the day of a long-distance relay race reported significantly less pain after the race compared to those who consumed a placebo.
Impact on Muscle Soreness and Recovery
Several studies have demonstrated the positive effects of cherry juice on muscle soreness and recovery:
A study by Howatson et al. (2010) found that marathon runners who consumed tart cherry juice for five days before, on the day of, and for 48 hours following a marathon showed significantly faster recovery of muscle strength compared to a placebo group.
Levers et al. (2015) reported that resistance-trained individuals who consumed powdered tart cherry for 10 days experienced reduced muscle soreness and improved recovery after intensive strength training.
The mechanisms behind these effects are thought to be related to the ability of cherry juice to reduce oxidative stress and inflammation, which are key factors in exercise-induced muscle damage and soreness.
Endurance Exercise Performance
Recent research has also suggested that cherry juice may enhance endurance exercise performance. A meta-analysis by Gao et al. (2020) examined the results of 10 studies and concluded that tart cherry supplementation significantly improved endurance exercise performance when consumed for 7 days or less prior to exercise.
The researchers hypothesized that this performance enhancement could be due to:
- Reduced inflammation and oxidative stress
- Improved muscle function and recovery
- Enhanced blood flow due to the nitrate content in cherries
While these findings are promising, it's important to note that more research is needed to fully understand the optimal dosage and timing of cherry juice consumption for performance enhancement.
Inflammation and Pain Reduction
The anti-inflammatory properties of cherry juice make it a promising natural remedy for various inflammatory conditions and associated pain.
Cherry Juice for Arthritis Management
Several studies have investigated the potential of cherry juice in managing arthritis symptoms:
A study by Schumacher et al. (2013) found that women with osteoarthritis who drank tart cherry juice twice daily for three weeks experienced significant reductions in markers of inflammation and reported less pain compared to those who received a placebo.
Kuehl et al. (2012) reported that tart cherry juice consumption reduced osteoarthritis pain and improved function in patients with knee osteoarthritis.
These effects are thought to be due to the ability of cherry anthocyanins to inhibit cyclooxygenase enzymes, which are involved in the inflammatory process, in a manner similar to some anti-inflammatory medications.
Mechanisms of Pain Reduction
The pain-reducing effects of cherry juice are primarily attributed to its anti-inflammatory properties. Kelley et al. (2018) outlined several mechanisms by which cherry juice may reduce pain:
- Inhibition of inflammatory enzymes (COX-1 and COX-2)
- Reduction of oxidative stress
- Modulation of inflammatory pathways
- Potential analgesic effects similar to some pain medications
These mechanisms suggest that cherry juice could potentially offer a natural alternative or complement to traditional pain management strategies for some individuals.
Potential Applications for Chronic Pain Conditions
While more research is needed, the anti-inflammatory and pain-reducing properties of cherry juice suggest potential applications for various chronic pain conditions:
Fibromyalgia: A small study by Elliott et al. (2020) found that tart cherry juice consumption improved sleep quality in individuals with fibromyalgia, which could indirectly help manage pain associated with this condition.
Lower back pain: While specific studies on cherry juice for back pain are limited, its general anti-inflammatory properties suggest potential benefits that warrant further investigation.
Neuropathic pain: Some animal studies have suggested that anthocyanins may have neuroprotective effects, which could potentially benefit individuals with neuropathic pain conditions.
It's important to note that while these potential applications are promising, more large-scale human studies are needed to confirm the efficacy of cherry juice for these conditions. Individuals with chronic pain should consult with healthcare professionals before using cherry juice as a complementary treatment.
Gout Management with Cherry Juice
Gout, a form of inflammatory arthritis characterized by sudden, severe attacks of pain, swelling, and redness in joints, has been a particular focus of cherry juice research. The potential benefits of cherry juice for gout management are primarily related to its ability to reduce uric acid levels in the body.
Uric Acid Reduction Properties
Elevated uric acid levels are the primary cause of gout. Several studies have investigated the effects of cherry consumption on uric acid levels:
Zhang et al. (2012) conducted a large-scale study involving 633 individuals with gout. They found that cherry intake over a two-day period was associated with a 35% lower risk of gout attacks compared with no intake.
A study by Collins et al. (2019) demonstrated that consuming tart cherry juice for four weeks led to a significant reduction in serum uric acid levels in adults with elevated levels.
The mechanism behind this uric acid reduction is thought to be related to the anthocyanins in cherries, which may inhibit xanthine oxidase, an enzyme involved in uric acid production.
Recommended Intake for Gout Prevention
While optimal dosage can vary depending on individual factors, most studies have used the following guidelines:
- Frequency: Daily consumption appears to be most effective for maintaining lower uric acid levels.
- Quantity: Studies have typically used 240-480 ml (8-16 ounces) of tart cherry juice per day.
- Duration: Benefits have been observed with both short-term (2-3 days during acute attacks) and long-term (4 weeks or more) consumption.
It's important to note that while these dosages have shown benefits in studies, individuals with gout should consult with a healthcare provider before using cherry juice as a complementary treatment.
Limitations and Precautions
While cherry juice shows promise for gout management, there are some important considerations:
Sugar content: Cherry juice contains natural sugars, which may be a concern for individuals with diabetes or those watching their calorie intake.
Interaction with medications: Cherry juice may interact with certain medications, particularly those used to treat gout (like allopurinol) or blood thinners.
Individual variability: The effectiveness of cherry juice may vary among individuals due to factors such as genetics, diet, and overall health status.
Not a replacement for medical treatment: While cherry juice may be beneficial, it should not replace prescribed medications or other treatments recommended by healthcare providers.
Individuals with gout or at risk of developing gout should discuss the potential use of cherry juice with their healthcare provider to ensure it's appropriate for their specific situation.
Cognitive Function and Cherry Juice
Emerging research suggests that cherry juice, particularly tart cherry juice, may have potential benefits for cognitive function. This is largely attributed to the high antioxidant content of cherries, particularly their anthocyanins.
Potential Neuroprotective Effects
The antioxidants in cherry juice, especially anthocyanins, have shown potential neuroprotective effects in various studies:
A study by Kent et al. (2017) found that tart cherry juice consumption was associated with improved cognitive performance in older adults with mild-to-moderate dementia.
Chai et al. (2019) demonstrated that tart cherry juice intake for 12 weeks improved cognitive performance and reduced systolic blood pressure and LDL cholesterol in older adults with normal cognitive function.
These neuroprotective effects are thought to be due to the ability of cherry anthocyanins to cross the blood-brain barrier and directly interact with neurons, potentially reducing oxidative stress and inflammation in the brain.
Memory and Cognitive Performance
Several studies have specifically looked at the effects of cherry juice on memory and cognitive performance:
Caldwell et al. (2015) found that young adults who consumed tart cherry juice for five days showed improved short-term memory and reduced mental fatigue during cognitive tests compared to those who received a placebo.
A study by Krikorian et al. (2010) on older adults with mild cognitive impairment showed that 12 weeks of tart cherry juice consumption was associated with improved verbal fluency and short-term and long-term memory.
While these results are promising, it's important to note that more large-scale, long-term studies are needed to fully understand the potential cognitive benefits of cherry juice.
Heart Health Benefits of Cherry Juice
Cherry juice, particularly tart cherry juice, has shown potential benefits for heart health in several studies. These benefits are largely attributed to the high antioxidant content of cherries, especially their anthocyanins and other polyphenols.
Blood Pressure Regulation
Several studies have investigated the effects of cherry juice on blood pressure:
Kent et al. (2017) found that older adults who consumed tart cherry juice for 12 weeks experienced a significant reduction in systolic blood pressure compared to those who received a placebo.
A study by Keane et al. (2016) showed that a single dose of tart cherry juice concentrate led to a peak reduction in systolic blood pressure of 7 mmHg three hours after consumption.
The mechanism behind this blood pressure-lowering effect is thought to be related to the ability of cherry polyphenols to improve endothelial function and increase the production of nitric oxide, a compound that helps relax blood vessels.
Cholesterol Management
Cherry juice may also have beneficial effects on cholesterol levels:
Chai et al. (2019) found that 12 weeks of tart cherry juice consumption led to significant reductions in LDL cholesterol and total cholesterol in older adults.
A study by Martin et al. (2010) on rats showed that tart cherry intake was associated with reduced total cholesterol and triglyceride levels.
These effects on cholesterol are likely due to the antioxidant and anti-inflammatory properties of cherry anthocyanins, which may help reduce oxidative stress and inflammation in the cardiovascular system.
Cardiovascular Risk Reduction
The combined effects of blood pressure regulation and cholesterol management suggest that cherry juice may have overall benefits for cardiovascular health:
A review by Kelley et al. (2018) concluded that the regular consumption of tart cherries or cherry juice may reduce the risk of cardiovascular disease by improving blood pressure, reducing inflammation, and enhancing antioxidant status.
Long-term consumption of cherry juice as part of a heart-healthy diet may contribute to overall cardiovascular risk reduction, although more long-term studies are needed to confirm this effect.
It's important to note that while these findings are promising, cherry juice should not be considered a replacement for prescribed medications or other treatments for cardiovascular conditions. Individuals with heart health concerns should consult with their healthcare provider before incorporating cherry juice into their diet as a complementary approach.
Immune System Support
Cherry juice, particularly tart cherry juice, may offer support to the immune system due to its rich nutrient profile and high antioxidant content.
Nutrient Profile for Immunity
Cherry juice contains several nutrients that are important for immune function:
- Vitamin C: A powerful antioxidant that supports various cellular
Conclusion
The comprehensive review of cherry juice benefits reveals a natural beverage with remarkable potential to support various aspects of human health. From improving sleep quality to aiding exercise recovery, managing inflammation, and potentially supporting heart and cognitive health, cherry juice - particularly tart cherry juice - has emerged as a promising functional food.
The sleep-enhancing properties of cherry juice, attributed to its melatonin and tryptophan content, offer a natural alternative for those struggling with sleep issues. Studies have consistently shown improvements in sleep duration and quality, making it a valuable consideration for individuals seeking non-pharmacological sleep aids (Pigeon et al., 2010; Losso et al., 2018).
In the realm of exercise recovery and performance, cherry juice's anti-inflammatory properties have demonstrated significant benefits. Research indicates its potential to reduce muscle soreness, accelerate strength recovery, and even enhance endurance performance (Connolly et al., 2006; Gao et al., 2020). These findings suggest that cherry juice could be a valuable addition to the nutritional strategies of athletes and fitness enthusiasts.
The anti-inflammatory effects of cherry juice extend beyond exercise recovery, showing promise in managing conditions such as arthritis and gout. Studies have reported reductions in pain and inflammation markers in individuals with osteoarthritis, as well as lower risks of gout attacks in those consuming cherry juice regularly (Schumacher et al., 2013; Zhang et al., 2012).
Emerging research also points to potential benefits for cognitive function and heart health. While more extensive studies are needed, initial findings suggest that the antioxidants in cherry juice may offer neuroprotective effects and support cardiovascular health by regulating blood pressure and cholesterol levels (Chai et al., 2019; Kent et al., 2017).
It's important to note that while these benefits are promising, cherry juice should not be considered a cure-all or a replacement for medical treatments. Individuals should consult with healthcare professionals before incorporating cherry juice into their diet, especially if they have existing health conditions or are taking medications.
As research continues, our understanding of cherry juice benefits will likely expand. Future studies may uncover additional health applications and refine our knowledge of optimal dosages and consumption patterns. For now, cherry juice stands as a testament to the potential health benefits found in natural, whole foods, offering a delicious way to potentially support overall health and wellbeing.
Connolly, D. A., McHugh, M. P., Padilla-Zakour, O. I., Carlson, L., & Sayers, S. P. (2006). Efficacy of a tart cherry juice blend in preventing the symptoms of muscle damage. British Journal of Sports Medicine, 40(8), 679-683.
Gao, R., Chilibeck, P. D., Zello, G. A., Awortwe, C., Gordon, J. B., & Chizen, D. R. (2020). The Effects of Tart Cherry Juice on Endurance Exercise Performance: A Meta-Analysis. Journal of the American Nutrition Association, 39(8), 724-733.
Kent, K., Charlton, K., Roodenrys, S., Batterham, M., Potter, J., Traynor, V., ... & Richards, R. (2017). Consumption of anthocyanin-rich cherry juice for 12 weeks improves memory and cognition in older adults with mild-to-moderate dementia. European Journal of Nutrition, 56(1), 333-341.
Losso, J. N., Finley, J. W., Karki, N., Liu, A. G., Prudente, A., Tipton, R., ... & Greenway, F. L. (2018). Pilot study of the tart cherry juice for the treatment of insomnia and investigation of mechanisms. American Journal of Therapeutics, 25(2), e194-e201.
Pigeon, W. R., Carr, M., Gorman, C., & Perlis, M. L. (2010). Effects of a tart cherry juice beverage on the sleep of older adults with insomnia: a pilot study. Journal of Medicinal Food, 13(3), 579-583.
Schumacher, H. R., Pullman-Mooar, S., Gupta, S. R., Dinnella, J. E., Kim, R., & McHugh, M. P. (2013). Randomized double-blind crossover study of the efficacy of a tart cherry juice blend in treatment of osteoarthritis (OA) of the knee. Osteoarthritis and Cartilage, 21(8), 1035-1041.
Zhang, Y., Neogi, T., Chen, C., Chaisson, C., Hunter, D. J., & Choi, H. K. (2012). Cherry consumption and decreased risk of recurrent gout attacks. Arthritis & Rheumatism, 64(12), 4004-4011.
Key Highlights and Actionable Tips
• Tart cherry juice may improve sleep quality and duration due to its melatonin and tryptophan content. Try consuming 240 ml twice daily, including 1-2 hours before bedtime.
• Cherry juice's anti-inflammatory properties may aid exercise recovery and reduce muscle soreness. Consider drinking it before and after intense workouts.
• The anthocyanins in cherry juice have shown potential to reduce inflammation and pain associated with conditions like arthritis and gout.
• Emerging research suggests cherry juice may support cognitive function and heart health by lowering blood pressure and cholesterol levels.
• When choosing cherry juice, opt for 100% pure juice without added sugars. Tart cherry varieties tend to have the highest concentration of beneficial compounds.
• Always consult your healthcare provider before using cherry juice as a complementary treatment, especially if you have existing health conditions or take medications.
How does cherry juice compare to whole cherries nutritionally?
While cherry juice retains many of the beneficial compounds found in whole cherries, it lacks the fibre content of the whole fruit. Cherry juice is more concentrated in certain nutrients and antioxidants, but whole cherries provide the added benefits of fibre for digestive health and blood sugar regulation. Both forms can be part of a healthy diet, but whole cherries may be preferable for those watching their sugar intake.
Can cherry juice interact with any medications?
Cherry juice may interact with certain medications, particularly blood thinners like warfarin. The high vitamin K content in cherries could potentially interfere with these medications. Additionally, cherry juice may interact with some diabetes medications and NSAIDs. It's crucial to consult with your healthcare provider about potential interactions before adding cherry juice to your routine if you're on any medications.
Are there any potential side effects of consuming cherry juice regularly?
While cherry juice is generally considered safe for most people, some potential side effects may include:
- Gastrointestinal discomfort due to its sorbitol content, especially in large amounts
- Increased risk of kidney stones in susceptible individuals due to its oxalate content
- Potential weight gain if consumed in excess due to its natural sugar content
Moderation is key, and it's advisable to start with small amounts to assess your tolerance.
How long does it typically take to see benefits from regular cherry juice consumption?
The timeframe for experiencing benefits can vary depending on the specific health outcome and individual factors. Some studies have shown improvements in sleep quality within 1-2 weeks of regular consumption. For exercise recovery and pain reduction, benefits have been observed within 7-10 days of consistent intake. However, for long-term benefits like improved cognitive function or heart health, consistent consumption over several months may be necessary. It's important to maintain realistic expectations and understand that results can vary among individuals.
Can cherry juice be used as a natural alternative to melatonin supplements for sleep?
While cherry juice, particularly tart cherry juice, contains natural melatonin, it shouldn't be considered a direct replacement for melatonin supplements. The melatonin content in cherry juice is generally lower and less consistent than in supplements. However, cherry juice may offer a more holistic approach to sleep improvement due to its combination of melatonin, tryptophan, and other beneficial compounds. Some individuals may find cherry juice effective for mild sleep issues, but those with chronic insomnia should consult a healthcare provider for appropriate treatment options.
References (Click to Expand)
Chai, S. C., Davis, K., Wright, R. S., Kuczmarski, M. F., & Zhang, Z. (2019). Impact of tart cherry juice on systolic blood pressure and low-density lipoprotein cholesterol in older adults: a randomized controlled trial. Food & Function, 10(10), 6317-6328. https://doi.org/10.1039/C9FO01482B
Connolly, D. A., McHugh, M. P., Padilla-Zakour, O. I., Carlson, L., & Sayers, S. P. (2006). Efficacy of a tart cherry juice blend in preventing the symptoms of muscle damage. British Journal of Sports Medicine, 40(8), 679-683. https://doi.org/10.1136/bjsm.2005.025429
Gao, R., Chilibeck, P. D., Zello, G. A., Awortwe, C., Gordon, J. B., & Chizen, D. R. (2020). The Effects of Tart Cherry Juice on Endurance Exercise Performance: A Meta-Analysis. Journal of the American Nutrition Association, 39(8), 724-733. https://doi.org/10.1080/07315724.2020.1713246
Kelley, D. S., Adkins, Y., & Laugero, K. D. (2018). A Review of the Health Benefits of Cherries. Nutrients, 10(3), 368. https://doi.org/10.3390/nu10030368
Kent, K., Charlton, K., Roodenrys, S., Batterham, M., Potter, J., Traynor, V., Gilbert, H., Morgan, O., & Richards, R. (2017). Consumption of anthocyanin-rich cherry juice for 12 weeks improves memory and cognition in older adults with mild-to-moderate dementia. European Journal of Nutrition, 56(1), 333-341. https://doi.org/10.1007/s00394-015-1083-y
Losso, J. N., Finley, J. W., Karki, N., Liu, A. G., Prudente, A., Tipton, R., Yu, Y., & Greenway, F. L. (2018). Pilot Study of the Tart Cherry Juice for the Treatment of Insomnia and Investigation of Mechanisms. American Journal of Therapeutics, 25(2), e194-e201. https://doi.org/10.1097/MJT.0000000000000584
Pigeon, W. R., Carr, M., Gorman, C., & Perlis, M. L. (2010). Effects of a tart cherry juice beverage on the sleep of older adults with insomnia: a pilot study. Journal of Medicinal Food, 13(3), 579-583. https://doi.org/10.1089/jmf.2009.0096
Schumacher, H. R., Pullman-Mooar, S., Gupta, S. R., Dinnella, J. E., Kim, R., & McHugh, M. P. (2013). Randomized double-blind crossover study of the efficacy of a tart cherry juice blend in treatment of osteoarthritis (OA) of the knee. Osteoarthritis and Cartilage, 21(8), 1035-1041. https://doi.org/10.1016/j.joca.2013.05.009
Zhang, Y., Neogi, T., Chen, C., Chaisson, C., Hunter, D. J., & Choi, H. K. (2012). Cherry consumption and decreased risk of recurrent gout attacks. Arthritis & Rheumatism, 64(12), 4004-4011. https://doi.org/10.1002/art.34677